Probiotic strains have been used in food products for hundreds of years and these Lactobacillus and Bifidobacteria strains are extremely safe. In the history of Natren, there have been no serious side effects in infants attributed to Natren’s probiotics.
When administering probiotic supplements to your child, be it through powders or mixed with a drink, ensure that the bacteria consumed will survive through the acid in your child’s stomach and make their way to the intestinal tract. Natren Inc. micro-enrobes its probiotic bacteria to survive the GI tract. Some of their probiotics products for pregnant and nursing women, babies, and children include
1Bullen, C., Tearle, P.V., and Willis, A.T., Bifidobacteria in the intestinal tract of infants: an in-vivo study, J. Med. Microbiol., 1976; 9:325-333.
2Bin-nun, A.; Bromiker, R.; Wilschansk, M.; Kaplan, M.; Rudensky, B.; Caplan, M.; Hammerman, C. Oral probiotics prevent necrotizing Enterocolitis in very low birth weight neonates. J of Ped 2005: 192-196
3Lee, M.C., Lin, L.H., Hung, K.L., and Wu, K.Y., Oral bacterial therapy promotes recovery from acute diarrhea in children, Acta. Paediatr. Taiwan, 2001; Sep-Oct;42(5):301-305.
4O’Mahony, L., McCarthy, J., Kelly, P., Hurley, G., Luo, F., Chen, K., O’Sullivan, G.C., Kiely, B., Collins, J. K., Shanahan, F., Quigley, E. M. Lactobacillus and Bifidobacterium in IBS: symptom responses and relationship to cytokine profiles. Gastroenterology, 2005; 128(3): 541-551
5DePalma, G., Cinova, J., Stepankova, R., Tuckova, L., Sanz, Y. Pivotal advance: Bifidobacteria and gram-negative bacteria differentially influence immune responses in the proinflammatory milieu of celiac disease in children, Journal of Leukocyte Biology 2010, 87: 000-000.
6Kim, H. S., and Gilliland, S. E. Lactobacillus acidophilus as a dietary adjunct for milk to aid lactose digestion in humans, J. Dairy Sci. 1983, 66: 959-966.
7Effect of the microbial lactase (EC 126.96.36.199) activity in yoghurt on the intestinal absorption of lactose: an in vivo study in lactase-deficient humans. B J Nutr. 1990, 64: 71-79.
8Chebbi, N.B., Chander, H., Ranganathan, B., Casein degredation and amino acid liberation in milk by two highly proteolytic strains of lactic acid bacteria, Acta Microbiol. Pol., 1977; 26(3):281-284.
9Pescuma M., et.al. Whey fermentation by thermophilic lactic acid bacteria: evolution of carbohydrates and protein content. Food Microbiology 2008;25:442-451
10Arunachalam, K. D. The organic acids produced by Bifidobacteria are thought to stimulate the intestinal peristalsis and help a normal bowel movement (pg 1575) 1999. Nutr. Res., 19(10): 1559-1597.
11Vivatvakin, B.; Kowitdamrong, E. Randomized control trial of live Lactobacillus acidophilus plus Bifidobacterium infantis in treatment of infantile acute watery diarrhea. J Med Assoc 2006.
12Bjorksten, B.; Sepp. E.; Julge, K.; Voor, T.; Mikelsaar, M. Allergy development and the intestinal microflora during the first year of life. J Allergy Clin Immunol 2008 Vol. 108: 516-520
13Ozdemir, O. Various effects of different probiotic strains in allergic disorders: an update from laboratory and clinical data. Clinical and Exp Immunology 2010. 1-10
14Gruber, C. et al. Reduced Occurrence of Early atopic Dermatitis. The Journal of Allergy and clinical Immunology 2010, 126(4): 791-797.
15Lee, J. et al. Meta-analysis of clinical trials of probiotics for prevention and treatment of pediatric atopic dermatitis. J Allergy Clin Immunol 2008, 121: 116-121.
16Hoyos, A.B. Reduced Incidence of Necrotizing Enterocolitis Associated with Enteral Administration of Lactobacillus acidophilus and Bifidobacterium infantis to Neonates in an Intensive Care Unit. Int J Infect Dis 1999 Vol. 3: 197-202.
17Picard C., Fioramonti J., Francois A., Robinson T., Neant F., and Matuchansky C., Review article: bifidobacteria as probiotic agents – Physiological effects and clinical benefits. Ailment Pharmacol Ther 2005; 22: 495-51
18Arunachalam, K. D., Role of bifidobacteria in nutrition, medicine and technology, Nutr. Res., 1999; 19(10): 1559-1597.
19Lin, H.C.; Su, B.H.; Chen, A.C.; Lin, T.W.; Tsai, C.H.; Yeh, T.F.; Oh, W. Oral Probiotics Reduce the Incidence and Severity of Necrotizing Enterocolitis in Very Low Birth Weight Infants. Pediatrics 2005 Vol. 115(1).
20Caplan, M. S., Jilling, T. Neonatal enterocolitis: possible role of probiotic supplementation. J Ped Gastroenterology and Nutr. 2000; 30:S18-22.