From Yogurt to Probiotics

Natren’s story is rooted in over 700 years of probiotic tradition, brought to the U.S. by Natasha Trenev and her family after fleeing political persecution in Yugoslavia. Founded in California, Natren became a pioneer in probiotic innovation—introducing live-culture yogurt to health food stores, inventing cold-pack shipping for perishable supplements, and setting the first industry standards for probiotic labeling. Natasha’s leadership helped shift probiotics from niche health foods to scientifically recognized essentials, earning global recognition from organizations like the World Health Organization. Today, Natren continues to lead the industry with precision, integrity, and unmatched probiotic quality.

About us image

Planting roots in the new soil

1955

Arriving in America

After more than a year of waiting, the family immigrated to the U.S. in 1955, settling briefly in Milwaukee with an uncle. Despite the warm welcome, they left nine months later in search of better opportunities.

1956

California Dreams

In late 1956, the family moved to Hollywood, California, with just $100 and no job offers, driven by the promise of a healthier lifestyle and greater opportunity.

Early 1960s

The Yogurt Revival

The founder’s father reentered the yogurt business with a mission to create the best probiotic yogurt in America. He imported their original live culture from Yugoslavia by personally arranging for a friend to bring it over.

1960s

Continental Culture Specialists Is Born

Launching in Glendale, California, the family founded Continental Culture Specialists, selling liquid yogurt by the gallon and solid yogurt in pints—before the era of flavored varieties.

About us image

Setting the probiotic standard

1980

Starting from the Garage

In 1980, Natasha gained access to a lab and began producing her own probiotic supplements—overseeing culturing and freeze-drying, and ultimately bottling herself. The business operated from her home, where they stored the product in their garage refrigerator and her husband delivered dry ice daily to preserve the live cultures in thermally controlled packaging and shipping.

1980s

Frustrated by Poor Industry Standards

Despite her efforts, Natasha was dismayed by the lack of quality control and standards in the dietary supplements industry. She was asked by the National Membership of the National Nutritional Foods Association to author the first standard in the dietary supplement industry of any kind. She was asked to write the Standard for Probiotic Product Labeling to stimulate other members to set more standards in other dietary supplement categories. Her probiotic labeling standard was voted on and accepted in July 1989 by an overwhelming vote of the entire NNFA membership.

1980s

Educating on Super Strains

Even well-known strains like L.acidophilus were being undermined by generic or mislabeled species and strains in probiotic supplements. Natasha emphasized the difference between scientifically validated super strains and unreliable formulas with little to no benefit.

1989

Establishing Industry Standards

Working with the Natural Nutritional Foods Association (NNFA), Natasha helped develop the first official probiotic labeling standard. Adopted in 1989, it required clear labeling of strain identity, cell counts, expiration, storage, and safety certifications—standards still largely unmet by competitors.

1993

Global Recognition

In 1993, Natasha was invited by the World Health Organization to speak at the Fifteenth International Congress of Nutrition in Australia. Her talk on probiotics earned a standing ovation from a room full of global scientists and medical professionals.

1994

Read into Congressional Record

Her Probiotic Labeling Standard were read into Congressional Record in order to facilitate the passing of the DSHEA Amendment. The standards were routinely ignored by the Dietary Supplement Industry thereafter.

  • 1200s
  • 1900s
  • 1941
  • 1954
  • 1955
  • 1956
  • 1960s
  • 1966
  • 1970
  • 1971
  • 1972
  • 1973
  • 1974
  • 1980
  • 1989
  • 1993
  • Nowadays

Where it all began

1200s to Early 1900s

Family Legacy Begins

The founder’s family has a probiotic yogurt-making heritage spanning over 700 years, with a unique, centuries-old culture passed down through generations.

Early 20th Century – 1941

Supplying Royalty

By the start of World War II, the family’s yogurt was so renowned that it was supplied to the royal family of Yugoslavia—until the monarchy was overthrown by Axis powers in 1941.

1941 – 1954

Loss and Exile

Following the war and the rise of Marshall Tito’s regime, the family faced persecution due to their royal ties. Their business was seized, and in 1954, they fled to Vienna to seek refuge.

1954

Seeking a New Start

In October 1954, the family applied to immigrate to the United States, marking the beginning of a new chapter for their probiotic legacy.

About us image

Humble beginnings

1966 - 1970

From Student to Innovator

In 1966, Natasha began studying at UCLA, where she met her future husband, Yordan Trenev. After graduating and marrying in 1970, she joined the family yogurt business full-time and helped create the Royal Yogurt line—honey-sweetened, fruit-flavored probiotic yogurts loved by many.

1970

Refrigeration Revolution

At a time when health food stores lacked refrigeration, Natasha convinced store owners to bring old home fridges into their shops to properly store live-culture yogurt—ensuring product quality and pioneering refrigerated probiotic sales.

1972

Smart Partnerships & Statewide Expansion

Natasha Trenev partnered with Hansen’s Juice to share delivery routes, reducing costs. She also spearheaded efforts to ship dairy products across state lines—navigating differing state standards to expand the reach of their probiotic yogurt.

1973

Pioneering Cold-Pack Air Shipping

To supply distributors in states like Pennsylvania and Florida, Natasha made a groundbreaking deal with United Airlines to ship live-culture yogurt in dry ice containers. This innovation helped normalize cold-pack shipping for perishables in the U.S.

1974

A New Scientific Mission

In 1974, Natasha left Continental Culture Specialists to focus on advanced research. Driven by a desire to understand the science behind probiotics, she began consulting for yogurt companies and diving into microbiological research and academic literature.

About us image

Natren starts the probiotic industry

1990s Onward

Probiotics Enter the Mainstream

The overwhelming response marked a turning point: the medical world was finally beginning to acknowledge the science behind daily probiotic use. Natasha predicted probiotics would one day be as widely accepted and understood as vitamins. She stills considers precision probiotic supplementation as the foundation of all health.

Natasha Trenev’s contributions to the field of probiotics

  • In 1970, pioneered perishable distribution and established refrigerated sections for natural yogurt with active yogurt starter strains in health food stores.
  • Founded Natren® in 1982 to manufacture the finest probiotic products worldwide.
  • Introduced the category of probiotics to the natural health food and dietary supplements industry, where probiotics were previously inappropriately labeled as "acidophilus products".
  • First to publish a book on probiotics geared to consumers, co-authored with Dr. Leon Chaitow, Probiotics: How Live Yogurt and Other "Friendly Bacteria" Can Restore Health and Vitality.
  • Published and authored the second definitive book on probiotic benefits: Probiotics: Nature's Internal Healers.
  • First manufacturer's representative to serve on the National Nutritional Foods Association NNFA Probiotic Standards Committee.
  • Responsible for establishing the probiotics category within the natural foods industry, later adopted by the nutraceutical and other food industries.
  • Authored the probiotic standard in 1993 for the Natural Product Quality Assurance Alliance, which became the basis for the book "Quality and Safety Standards" in 1995. Senator Orin Hatch's group read this book into the Congressional Record.
  • Published her fourth book. The Power of Probiotics: The Secrets to Great Health in 2006

Natren's Proprietary Thermally Controlled Delivery System

  • Live probiotics need cold-chain delivery.
  • Heat exposure during transit can kill them before they reach you.